Abstract
EXPERIMENTAL evidence has been put forward recently to support the hypothesis1 that mitotic homeostasis is controlled by tissue-specific but not species-specific factors which can be isolated from homogenates of the corresponding tissues1–4. We have looked for such a substance in lymphoid tissue. The effect of lymph node extracts on DNA synthesis in lymphocytes has also been tested.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Bullough, W. S., and Lawrence, E. B., Nature, 220, 134 (1968).
Suinnet, J. D., and Chopia, D. P., Nature, 222, 1189 (1969).
Saetren, H., Exp. Cell Res., 11, 229 (1956).
Rytomaa, T., and Kiviniemi, K., Cell Tissue Kinetics, 1, 341 (1968).
Moorhead, J. F., and McFarland, W., Nature, 211, 1157 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MOORHEAD, J., PARASKOVA-TCHERNOZENSKA, E., PIRRIE, A. et al. Lymphoid Inhibitor of Human Lymphocyte DNA Synthesis and Mitosis in vitro. Nature 224, 1207–1208 (1969). https://doi.org/10.1038/2241207a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/2241207a0
This article is cited by
-
Humorale Regulatoren der Zellproliferation in der H�matopoese
Klinische Wochenschrift (1980)
-
Inhibition or augmentation of PHA-induced lymphocyte transformation by factors of cultured lymphoblastoid cell lines
Experientia (1979)
-
An endogenous inhibitor of fibroblast proliferation hinders simian virus 40 replication
Naturwissenschaften (1979)
-
The effects of fractions (chalones) obtained from lymphoid organs on the immune response in vivo
Agents and Actions (1978)
-
The effects of fractions (Chalones) obtained from lymphoid organs on lymphocyte proliferation in vitro
Agents and Actions (1977)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.