Abstract
Chapman and McLauchlan1 reported that the proton magnetic resonance (PMR) spectrum of the rabbit sciatic nerve exhibited a doublet structure with the spacing between components showing an angular dependence of the form (3 cos2 θ−1), where θ was the angle between the sample axis and the direction of the external magnetic field. They suggested that this splitting arises from the direct dipole–dipole interaction between the two protons of the water molecules which is not averaged to zero because of partial orientation of the bulk water within the nerve2. If this interpretation is correct, it would be of interest for the information it provides about the internal organization of the nerve tissue.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Chapman, G., and McLauchlan, K. A., Nature, 215, 392 (1967).
Buckingham, A. D., and McLauchlan, K. A., Progress in NMR Spectroscopy, 2, 63 (Pergamon Press, 1967).
Hughes, A. M., and Calvin, M., Science, 127, 1445 (1958).
Jackson, J. A., and Rabideau, S. W., J. Chem. Phys., 41, 4008 (1964).
Pake, G. E., J. Chem. Phys., 16, 327 (1948).
Fritz, O. G., and Swift, T. J., Biophys. J., 7, 675 (1967).
Cope, F. W., Biophys. J., 9, 303 (1969).
Meiboom, S., J. Chem. Phys., 34, 375 (1960).
Lawson, K. D., and Flautt, T. J., J. Amer. Chem. Soc., 89, 5489 (1967).
Feher, G., and Knight, W. D., Rev. Sci. Instrum., 26, 293 (1955); Reilly, C. A., McConnell, H., and Meisenheimer, R. G., Phys. Rev., 98, 264A (1955); Klein, M. P., and Holder, B. E., ibid., 98, 265A (1955).
Carr, H. Y., and Purcell, E. M., Phys. Rev., 94, 630 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KLEIN, M., PHELPS, D. Evidence against Orientation of Water in Rat Phrenic Nerve. Nature 224, 70–71 (1969). https://doi.org/10.1038/224070a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/224070a0
This article is cited by
-
Neutron scattering from water in DNA and muscle tissue
Journal of Biological Physics (1980)
-
Unjustified Doubts about the Nuclear Magnetic Resonance Demonstration of Structured Water in Neural and Muscle Tissue
Nature New Biology (1972)
-
Dielectric and semiconductive behaviors of solvated biomacromolecules
Journal of Bioenergetics (1970)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
