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IgA with “Secretory Piece” in Bovine Colostrum and Saliva

Abstract

WE have shown that in bovine colostrum and saliva there is a secretory IgA with a sedimentation, coefficient of 11S and a secretory piece, previously unknown and comparable with the 11S IgA described in human and rabbit external secretions. These secretory IgA contain molecules of 7S IgA with an additional protein segment called the transport or secretory piece1–5. Furthermore, the free form of the secretory piece is identified in bovine colostrum and also in mature milk which contains very little IgA.

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MACH, JP., PAHUD, JJ. & ISLIKER, H. IgA with “Secretory Piece” in Bovine Colostrum and Saliva. Nature 223, 952–955 (1969). https://doi.org/10.1038/223952a0

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