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On Comparison of Interactions of a “Bitter-sensitive Protein ” from Porcine Tongues with Human Taste Thresholds

Abstract

Doig, Lopiekes and I earlier reported the interactions of a porcine protein fraction with bitter compounds1. Price has recently commented on the poor agreement of our data with, as he states, “characteristics which might be expected of ‘the bitter-receptor protein’”2. I would like to make the following comments on comparisons drawn between porcine association constants and human bitter-threshold values.

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References

  1. Dastoli, F. R., Lopiekes, D. V., and Doig, A. R., Nature, 218, 884 (1968).

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  2. Price, S., Nature, 221, 779 (1969).

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  3. Kare, M. R., and Ficken, M. S., in Olfaction and Taste (edit. by Zotterman, Y.) (Macmillan Co., London, 1963).

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  4. Pfaffman, C., in Handbook of Physiology, 1, 507 (1959).

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  5. Horowitz, R. M., in Biochemistry of Phenolic Compounds (edit. by Harborne, J. F.) (Academic Press, 1964) and Merck Index, seventh ed., 708 (Merck and Co. Inc., Rahway, NJ, 1960).

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DASTOLI, F. On Comparison of Interactions of a “Bitter-sensitive Protein ” from Porcine Tongues with Human Taste Thresholds. Nature 223, 524–525 (1969). https://doi.org/10.1038/223524b0

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