Abstract
In a cell-free system programmed with MS2 phage RNA, native 50S and 30S ribosomes are involved in initiation. After completion of a round of synthesis the ribosomes dissociate to yield 30S and 50S subunits capable of reinitiation. Reinitiation in vitro is associated with subunit exchange.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Nakada, D., and Kaji, A., Proc. US Nat. Acad. Sci., 57, 128 (1967).
Mangiarotti, G., and Schlessinger, D., J. Mol. Biol., 20, 123 (1966).
Nomura, M., and Lowry, C., Proc. US Nat. Acad. Sci., 58, 946 (1967).
Nomura, M., Lowry, C., and Guthrie, C., Proc. US Nat. Acad. Sci., 58, 1487 (1967).
Guthrie, C., and Nomura, M., Nature, 219, 232 (1968).
Gosh, H. P., and Khozana, H. G., Proc. US Nat. Acad. Sci., 58, 2455 (1967).
Anderson, J. S., Bretscher, M. S., Clark, B. F. C., and Marcker, K. A., Nature, 215, 490 (1967).
Iwaski, K., Sabol, S., Wahba, A. J., and Ochoa, S., Arch. Biochem. Biophys., 125, 542 (1968).
Mukundan, M. A., Hershey, J. W. B., Dewey, K. F., and Thach, R. E., Nature, 217, 1013 (1968).
Revel, M., Lelong, J. C., Brawerman, G., and Gros, F., Nature, 219, 1016 (1968).
Kondo, M., Eggerston, G., Eisenstadt, J., and Lengyel, P., Nature, 220, 368 (1968).
Kaempfer, R. O., Meselson, M., and Raskas, H. J., J. Mol. Biol., 31, 277 (1968).
Kaempfer, R. O., Proc. US Nat. Acad. Sci., 61, 106 (1968).
Sugiyama, T., and Nakada, D., Proc. US Nat. Acad. Sci., 57, 1744 (1967).
Sugiyama, T., and Nakada, D., J. Mol. Biol., 31, 431 (1968).
Eisenstadt, J. M., and Brawerman, G., Proc. US Nat. Acad. Sci., 58, 1560 (1967).
Parenti-Rosima, R., Eisenstadt, A., and Eisenstadt, J. M., Nature, 221, 363 (1969).
Schlessinger, D., Mangiarotti, G., and Apirion, D., Proc. US Nat. Acad. Sci., 58, 1782 (1967).
Capecchi, M. R., Proc. US Nat. Acad. Sci., 58, 1144 (1967).
Caskey, C. T., Tompkins, R., Scolnick, E., Caryk, T., and Nirenberg, M., Science, 162, 135 (1968).
Scolnick, E., Tompkins, R., Caskey, T., and Nirenberg, M., Proc. US Nat. Acad. Sci., 61, 768 (1968).
Kohler, R. E., Ron, E. Z., and Davis, B. D., J. Mol. Biol., 36, 71 (1968).
Subramanian, A. R., Ron, E. Z., and Davis, B. D., Proc. US Nat. Acad. Sci., 61, 761 (1968).
Algranati, I. D., Gonzalez, N. S., and Bade, E. G., Proc. US Nat. Acad. Sci., 62, 574 (1969).
Adams, J. M., and Capecchi, M. R., Proc. US Nat. Acad. Sci., 55, 147 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GRUBMAN, M., NAKADA, D. Ribosomal Subunits and MS2 Phage RNA-directed Protein Synthesis. Nature 223, 1242–1247 (1969). https://doi.org/10.1038/2231242a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/2231242a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
