Abstract
OBSERVATIONS made by Okazaki et al.1,2 and Oishi3 support the idea that relatively small polydeoxynucleotides are intermediates in the replication of strands of both bacterial and phage DNA. The polydeoxynucleotides are subsequently joined to each other and to the growing DNA strands. This mechanism would allow a single kind of DNA polymerase to copy both parental DNA strands in the 5′ to 3′ direction.
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References
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TSUKADA, K., MORIYAMA, T., LYNCH, W. et al. Polydeoxynucleotide Intermediates in DNA Replication in Regenerating Liver. Nature 220, 162–164 (1968). https://doi.org/10.1038/220162a0
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DOI: https://doi.org/10.1038/220162a0
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