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In vivo Antibody Production by Spleen Cells after Incubation in vitro with Heterologous Antilymphocyte Plasma

Nature volume 220, pages 1350–1352 (1968)Cite this article

Abstract

SOME heterologous antilymphocyte serum (ALS) and plasma (ALP) preparations have immunosuppressive properties1–5 while others, produced in an identical manner, completely lack this activity5. At present, no in vitro standardization test correlates well with the immunosuppressive potency of ALS or ALP as determined by its ability to prolong allograft survival5–7. The series of experiments reported here could provide a rational basis for the development of such a test.

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Authors and Affiliations

  1. Department of Experimental Surgery, McGill University, Montreal, Canada

    H. F. JEEJEEBHOY & A. G. RABBAT

Authors
  1. H. F. JEEJEEBHOY
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  2. A. G. RABBAT
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JEEJEEBHOY, H., RABBAT, A. In vivo Antibody Production by Spleen Cells after Incubation in vitro with Heterologous Antilymphocyte Plasma. Nature 220, 1350–1352 (1968). https://doi.org/10.1038/2201350a0

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