Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Effect of Antiserum to E. coli DNA Polymerase on Synthesis of ΦXI74 DNA in Extracts of ΦX-Infected Cells

Nature volume 220, pages 131–134 (1968)Cite this article

Abstract

In vitro synthesis of ΦX DNA in extracts of ΦX-infected cells is at least in part the same as the normal in vivo process. It seems that a bacterial enzyme plays a part in the synthesis of single stranded DNA (both in vivo and in extracts), but that this enzyme is not simply the enzyme isolated by Kornberg from E. coli.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Denhardt, D. T., and Burgess, A. B., Cold Spring Harbor Symp. Quant. Biol., 33 (in the press).

  2. Dressler, D. H., and Denhardt, D. T., Nature, 219, 346 (1968).

    Article  ADS  CAS  Google Scholar 

  3. Lindqvist, B. H., and Sinsheimer, R. L., J. Mol. Biol., 32, 285 (1968).

    Article  CAS  Google Scholar 

  4. Knippers, R., Komano, T., and Sinsheimer, R. L., Proc. US Nat. Acad. Sci., 59, 577 (1968).

    Article  ADS  CAS  Google Scholar 

  5. Komano, T., Knippers, R., and Sinsheimer, R. L., Proc. US Nat. Acad. Sci., 59, 911 (1968).

    Article  ADS  CAS  Google Scholar 

  6. Denhardt, D. T., Biochem. Biophys. Res. Commun., 23, 641 (1966).

    Article  CAS  Google Scholar 

  7. Steinberg, R. A., and Denhardt, D. T., J. Mol. Biol. (in the press).

  8. Huh, T. Y., and Helleiner, C. W., Biochim. Biophys. Acta, 155, 107 (1968).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Biological Laboratories, Harvard University, Cambridge, Massachusetts

    DAVID T. DENHARDT

Authors
  1. DAVID T. DENHARDT
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

DENHARDT, D. Effect of Antiserum to E. coli DNA Polymerase on Synthesis of ΦXI74 DNA in Extracts of ΦX-Infected Cells. Nature 220, 131–134 (1968). https://doi.org/10.1038/220131a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/220131a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing