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Effects of Testosterone Analogues on Interferon Formation, Induction of Antiviral Protein and Synthesis of Cell Protein in Tissue Culture

Abstract

INTERFERON, an antiviral protein produced by cells in response to penetration of viruses or other agents, has been extensively studied. It is known that anabolic hormones affect protein synthesis and that production and activity of interferon are sensitive to the action of inhibitors of protein synthesis1–3. Some work has been published on the influence of hormones on the production and activity of interferon, but the effects of hormones on these processes and on protein synthesis have not been compared4–6.

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ZEITLENOK, N., ROIHEL, V. & GORBACHKOVA, E. Effects of Testosterone Analogues on Interferon Formation, Induction of Antiviral Protein and Synthesis of Cell Protein in Tissue Culture. Nature 219, 978–979 (1968). https://doi.org/10.1038/219978a0

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