Abstract
STIMULATION studies have suggested that the septal region1,2 of many mammals affects behavioural reactions. In rats bilateral lesions of the septal nuclei produce an acute typical reaction resembling aggression which lasts from 24 to 48 h3. Septal hyper-irritability after electrical stimulation has been reported to last from 7 to 14 days3. Amygdaloid lesions appear to inhibit the septal reaction in the rat and it is believed that these two structures may have opposite functions in the control of emotional behaviour, at least in rats4.
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References
Olds, J., Science, 127, 315 (1958).
Hunsperger, R. W., and Bucher, V. M., Prog. Brain Res., 27, 103 (1967).
Heller, A., Harvey, J. A., and Moore, R. Y., Biochem. Pharmacol., 11, 859 (1962).
Zeman, W., and Innes, J. R. M., Craigie's Neuroanatomy of the Rat (Academic Press, New York, 1963).
Reinhard, J. F., Plekss, O. J., and Sendi, J. F., Proc. Soc. Exp. Biol. and Med., 104, 480 (1960).
Haley, T. J., Acta Pharmacol. Toxicol., 13, 107 (1957).
Sacchi, U., Bonamine, F., Dolce, G., and Garello, L., Boll. Soc. Ital. Biol. Sper., 31, 665 (1955).
King, F. A., J. Nerv. Ment. Dis., 126, 57 (1958).
Delgado, J. M. R., Psychiat. Res., 12, 259 (1960).
Falck, B., Hillarp, N. A., Thieme, G., and Torp, A., J. Histochem. Cytochem., 10, 348 (1962).
Falck, B., and Owman, C., Acta Univ. Lund. II, No. 7 (1965).
Dahlström, A., and Fuxe, K., Acta Physiol. Scand., 62, Suppl. 232 (1964).
de la Torre, J. C., Médicine et Hygiène, Thesis No. 14, 77, Geneva (1968).
Rothlin, E., in Psychotropic Drugs (edit. by Garattini, S., and Ghetti, V.), 36 (Elsevier, Amsterdam, 1957).
Freedman, D. X., Amer. J. Psychiat., 119, 843 (1963).
Olds, J., Killam, K. F., and Eiduson, S., in Psychotropic Drugs (edit. by Garattini, S., and Ghetti, V.), 235 (Elsevier, Amsterdam, 1957).
Taeschler, M., in Neuropsychopharmacology (edit. by Brill, H.), 393 (Excerpta Medica Foundation, Amsterdam, 1967).
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DE LA TORRE, J. Effect of LSD-25 on the Septal Region of the Rat Brain. Nature 219, 954–955 (1968). https://doi.org/10.1038/219954a0
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DOI: https://doi.org/10.1038/219954a0
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