Abstract
THE ependyma lining the third ventricle, particularly in the hypothalamus, shows regional differences in structure1. Following optical and electron microscopic examination of “atypical” ependymal cells in the third ventricle, it was suggested that some of them secrete into the cerebrospinal fluid (CSF) while others have a sensory function2. These observations have led to the hypothesis that the CSF acts as a vehicle for chemical information in integrating the hypothalamo-hypophysial system3.
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KUMAR, T., THOMAS, G. Metabolites of 3H-Oestradiol-17β in the Cerebrospinal Fluid of the Rhesus Monkey. Nature 219, 628–629 (1968). https://doi.org/10.1038/219628a0
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DOI: https://doi.org/10.1038/219628a0
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