Abstract
HOARD et al. have put forward the hypothesis that there are differences between the structure of the haem group in low-spin and high-spin haem compounds1. In high-spin metmyoglobin the iron atom is not coplanar with the haem group2, and X-ray analysis at atomic resolution of one other high-spin porphyrin compound suggests that this may be a general structural feature of such compounds1,3. Hoard et al. suggested that in low-spin haem compounds the iron atom and haem plane would be more nearly coplanar than in high-spin compounds1. The recent determination of the structure of low-spin cyanide metmyoglobin is in accord with this suggestion (my unpublished work).
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References
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BRETSCHER, P. Models for Haem-Haem Interaction. Nature 219, 606–607 (1968). https://doi.org/10.1038/219606a0
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DOI: https://doi.org/10.1038/219606a0
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