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Kinetics of Death induced by Penicillin and Chloramphenicol in Synchronous Cultures of Escherichia coli

Abstract

THE technique of synchronous culture permits the study of sensitivity to antibacterial agents in a population of cells all at the same stage in the division cycle. The phenol sensitivity of Escherichia coli has been investigated in this way1, and the results obtained indicated that the cells showed maximum sensitivity during division and that sensitivity decreased during the period before the next division.

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MATHISON, G. Kinetics of Death induced by Penicillin and Chloramphenicol in Synchronous Cultures of Escherichia coli. Nature 219, 405–407 (1968). https://doi.org/10.1038/219405a0

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