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Reversal of PHA-induced Blastogenesis in Human Lymphocyte Cultures

Abstract

THE blastogenic action of phytohaemagglutinin (PHA) on human lymphocytes in culture has been well documented1–4. Some of the metabolic events which accompany this transformation, for example, DNA, RNA and protein synthesis, have also been extensively studied5–9. Such investigations have generally used cultures of lymphocytes or leucocytes in which the cells were continuously exposed to PHA.

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POLGAR, P., KIBRICK, S. & FOSTER, J. Reversal of PHA-induced Blastogenesis in Human Lymphocyte Cultures. Nature 218, 596–597 (1968). https://doi.org/10.1038/218596a0

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