Abstract
TREATMENT of urinary infections caused by Gram negative bacteria is often very difficult. It is frequently necessary to administer antibiotics in large doses, which presents a hazard to patients with impaired renal function. In many cases relapses occur as a result of bacterial resistance1. This study was undertaken to establish in vitro a synergistic combination of antibiotics against several strains of E. coli isolated from urinary infections.
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References
Mccare, W. R., and Jackson, G. G., New Engl. J. Med., 272, 1037 (1965).
Koch, W., and Kaplan, D., Nature, 203, 896 (1964).
Kaplan, D., and Koch, W., Nature, 209, 718 (1966).
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KAPLAN, D., KOCH, W. Synergistic Effect of Combinations of Cephalothin and Kanamycin on Strains of E. coli. Nature 218, 1165–1166 (1968). https://doi.org/10.1038/2181165a0
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DOI: https://doi.org/10.1038/2181165a0
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