Abstract
HUMAN chorionic gonadotrophin (HCG) has been detected by various bioassay procedures in the cerebrospinal fluid of pregnant and non-pregnant subjects with a high concentration of the hormone in the plasma and urine1–5. It was not detected in the cerebrospinal fluid when the plasma and urine concentrations were lower. In agreement with these earlier workers, McCormick6 and Tashima et al.7 concluded that HCG did not appear in the cerebrospinal fluid until a high threshold value, equivalent to a urinary excretion rate of about 250,000 IU of HCG/day, was exceeded.
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BAGSHAWE, K., ORR, A. & RUSHWORTH, A. Relationship between Concentrations of Human Chorionic Gonadotrophin in Plasma and Cerebrospinal Fluid. Nature 217, 950–951 (1968). https://doi.org/10.1038/217950a0
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DOI: https://doi.org/10.1038/217950a0
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