Abstract
Small amounts of nicotine injected intravenously usually increased the lever pressing activity of rats and caused a change in the EEG of cats indicative of cortical activation. These results in experimental animals are consistent with the subjective impression of some smokers that inhalation of tobacco smoke causes them to be more alert and efficient.
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ARMITAGE, A., HALL, G. & MORRISON, C. Pharmacological Basis for the Tobacco Smoking Habit. Nature 217, 331–334 (1968). https://doi.org/10.1038/217331a0
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DOI: https://doi.org/10.1038/217331a0
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