Abstract
I HAVE studied the chromosomal aberrations which are induced in mouse hepatocytes by single and fractionated doses of X-rays given at various times before or after surgical partial hepatectomy. The data presented here show that the different phases of the cell cycle possibly differ not only in their sensitivity to chromosomal damage by radiation but also in their ability to recover from such damage.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Wilson, M. E., Tsuboi, K. K., and Stowell, R. E., Cancer Res., 13, 80 (1953).
Jackson, J., Anat. Res., 134, 365 (1959).
Albert, M. D., J. Nat. Cancer Inst., 20, 309 (1958).
Stevenson, K. G., and Curtis, H. J., Rad. Res., 15, 774 (1961).
Shapiro, I. M., Intern. J. Rad. Biol., 3, 293 (1963).
Albert, M. D., and Bucher, N. L. R., Cancer Res., 20, 1514 (1960).
Weinbren, K., and Cohen, M., Brit. J. Radiol., 33, 419 (1960).
Holmes, B. E., Ionising Radiation and Cell Metabolism, Ciba Foundation Symposium (edit. by Wolstenholrae, G. E. W.), 225 (1956).
Shapiro, I. M., Yarmonenko, S. P., and Paliga, G. F., Nature, 203, 315 (1963).
Curtis, H. J., and Crowley, C., Rad. Res., 19, 331 (1963).
Doida, Y., Sugahara, T., and Horikawa, M., Rad. Res., 26, 69 (1965).
Evans, H. J., Radiation Research (edit. by Silini, G.), 482 (North-Holland Publ. Co., Amsterdam, 1967).
Lajtha, L. G., and Gilbert, C. W., Adv. in Biol. and Medical Physics, 1 (Acad. Press, 1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
COGGLE, J. Effect of Cell Cycle on Recovery from Radiation Damage in the Mouse Liver. Nature 217, 180–182 (1968). https://doi.org/10.1038/217180a0
Received:
Revised:
Published:
Issue Date:
DOI: https://doi.org/10.1038/217180a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.