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Immediate Circulatory Response to High Altitude Hypoxia in Man

Abstract

ACUTE mountain sickness and high altitude pulmonary oedema are two acute medical problems for troops in the Himalayan terrain who frequently shuttle between sea level and high altitudes (10,000–16,000 ft.). These two acute illnesses have some features in common: time lag (they rarely occur within 12 h of arrival at the altitude or 96 h after arrival), throbbing headache, muscular cramps and pulmonary congestion. We have studied the acute circulatory response to high altitude hypoxia and investigated the extent to which shifts in the circulating blood volumes, if any, could be related to the time lag and clinical features of these acute illnesses.

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ROY, S., GULERIA, J., KHANNA, P. et al. Immediate Circulatory Response to High Altitude Hypoxia in Man. Nature 217, 1177–1178 (1968). https://doi.org/10.1038/2171177a0

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