Abstract
THE electron probe microanalyser makes possible rapid, precise localization and quantitation of elements in thin biological tissue during visual scanning of specimens. This communication describes a study of its use in analysis of the metal content of normal and malignant blood cells. The instrument used (Cameca, Paris) had an optical magnification of 400 diameters with a resolving power of about 0.5µ. The X-ray spectrographs use quartz crystals which are bent and ground to a focusing circle of 250 mm radius. Detectors are proportional counters; one with a beryllium window and another of gas-flow type with a thin plastic window.
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References
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CARROLL, K., TULLIS, J. Observations on the Presence of Titanium and Zinc in Human Leucocytes. Nature 217, 1172–1173 (1968). https://doi.org/10.1038/2171172a0
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DOI: https://doi.org/10.1038/2171172a0
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