Abstract
THE respiratory quotient is an established guide for deducing the main class of substrate which is completely oxidized by the intact aerobic organism1. Incomplete oxidation of substrates has, however, been shown to occur in vivo in individual organs, such as kidney2,3 and heart4, and so an interpretation of the respiratory quotient cannot be made for observations of gaseous metabolism in an isolated tissue or a single organ without simultaneous evidence of complete substrate oxidation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Lusk, G., The Elements of the Science of Nutrition, fourth ed. (W. B Saunders and Company, Philadelphia, 1928).
Cohen, J. J., Amer. J. Physiol., 199, 560 (1960).
Cohen, J. J., Renal Metabolism and Epidemiology of some Renal Diseases (edit. by Metcoff, J.), 126 (National Kidney Disease Foundation, New York, 1964).
Bing, R. J., Siegel, A., Unger, I., and Gilber, M., Amer. J. Med., 16, 504 (1954).
Maffly, R. H., and Coggins, C. H., Nature, 206, 197 (1965).
Fruton, J. S., and Simmonds, S., General Biochemistry, second ed. (John Wiley and Sons, Inc., New York, 1958).
McCann, W. P., Gulati, O. D., and Stanton, H. C., Bull. Johns Hopkins Hosp., 108, 38 (1961).
Chinard, F. P., Enns, T., Nolan, M. F., Circulat. Res., 10, 473 (1962).
Nieth, H. E., Stein, E., and Marx, H. H., Verh. Dtsch. Ges. Inn. Med., 70, 684 (1964).
Shaloub, R., Webber, W., Glabman, S., Canessa-Fisher, M., Klein, jun., deHaas, J., and Pitts, R. F., Amer. J. Physiol., 204, 181 (1963).
Nieth, H., and Schollmeyer, P., Nature, 209, 1244 (1966).
Owen, E. E., and Robinson, R. R., J. Clin. Invest., 42, 263 (1963).
Gold, M., and Spitzer, J. J., Amer. J. Physiol., 206, 153 (1964).
Cohen, J. J., and Randall, E. W., Amer. J. Physiol., 206, 383 (1964).
Cohen, J. J., The Physiologist, 1, 9 (1958).
Cohen, J. J., and Wittmann, E., Amer. J. Physiol., 204, 795 (1963).
Selleck, B. H., and Cohen, J. J., Amer. J. Physiol., 208, 24 (1965).
Maffly, R. H., and Edelman, I. S., J. Gen. Physiol., 46, 733 (1963).
Chinard, F. P., Taylor, W. R., Nolan, M. F., and Enns, T., Amer. J. Physiol., 196, 535 (1959).
Herndon, R. F., and Freeman, S., Amer. J. Physiol., 192, 369 (1958).
Sharp, G. W. G., and Leaf, A., Proc. US Nat. Acad. Sci., 52, 1114 (1964).
Sharp, G. W. G., and Leaf, A., J. Biol. Chem., 240, 4816 (1965).
Skjelkvale, L., Nieder, V. K., and Huf, E. G., J. Cell Comp. Physiol., 56, 43 (1960).
Van Bruggen, J. T., and Zerahn, K., Nature, 188, 499 (1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
COHEN, J. Significance of Respiratory Quotients in Toad Bladder and Kidney. Nature 216, 399–400 (1967). https://doi.org/10.1038/216399a0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1038/216399a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
