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Heritable Resistance to Warfarin in Rats

Abstract

WARFARIN and other anticoagulants are used for the destruction of rats throughout the world and have been by far the most successful materials ever introduced for this purpose. Since 1960, however, apparently independent outbreaks of resistance to warfarin in Rattus norvegicus have been reported from Scotland1, Denmark2 and Wales3.

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References

  1. Boyle, C. M., Nature, 188, 517 (1960).

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  2. Lund, M., Nature, 203, 778 (1964).

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  3. Drummond, D. C., and Bentley, E. W., Report of the International Conference on Rodents and Rodenticides (E. P. P. O., Paris, 1967).

  4. O'Reilly, R. A., and Aggeler, P. M., Fed. Proc., 24, 1266 (1965).

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GREAVES, J., AYRES, P. Heritable Resistance to Warfarin in Rats. Nature 215, 877–878 (1967). https://doi.org/10.1038/215877a0

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