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Reduction in the Concentration of Phosphatidyl Serine in the Plasma of Birds with Avian Erythroblastosis

Abstract

PLASMA α-lipoprotein, obtained from birds affected with erythroblastosis, shows a slower than normal mobility in starch gel and paper electrophoresis. The protein moiety had the same electrophoretic mobility when it was derived from lipoproteins isolated by ultracentrifugation from the plasma of either normal or erythroblastotic birds1–3. This suggests that the change is in the lipid moiety. We have now observed a difference between lipid extracts of normal and leukaemic plasma involving a phospholipid with the same chromatographic behaviour on silica gel H as phosphatidyl serine.

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References

  1. Darcel, C. le Q., Canad. J. Biochem. Physiol., 38, 383 (1960).

    Article  CAS  Google Scholar 

  2. Merriman, M., and Darcel, C. le Q., Canad. J. Biochem., 42, 293 (1964).

    Article  CAS  Google Scholar 

  3. Merriman, M., and Darcel, C. le Q., Canad. J. Biochem., 43, 1667 (1965).

    Article  CAS  Google Scholar 

  4. Bligh, E. G., and Dyer, W. J., Canad. J. Biochem. Physiol., 37, 911 (1959).

    Article  CAS  Google Scholar 

  5. Skipski, V. P., Peterson, R. F., Saunders, J., and Barclay, M. J., Lipid Res., 4, 227 (1963).

    CAS  Google Scholar 

  6. Nichols, B., Lab. Pract., 13, 299 (1964).

    CAS  Google Scholar 

  7. Randerath, K., Thin-Layer Chromatography (Academic Press, New York, 1964).

    Google Scholar 

  8. Skidmore, W. D., and Entenman, C., J. Lipid Res., 3, 471 (1962).

    CAS  Google Scholar 

  9. Sakagami, T., Shimjo, T., and Yokoyama, A., J. Biochem. (Japan), 46, 1607 (1959).

    Article  CAS  Google Scholar 

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DARCEL, C. Reduction in the Concentration of Phosphatidyl Serine in the Plasma of Birds with Avian Erythroblastosis. Nature 215, 647–648 (1967). https://doi.org/10.1038/215647a0

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  • DOI: https://doi.org/10.1038/215647a0

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