Abstract
DNA is combined, as nucleohistone, with histone proteins in the chromosomes and nuclei of all cells except bacteria. It has been suggested that histones are involved in regulating gene function1,2. The molecular structure of nucleohistone is basic to the structure of chromosomes. X-ray diffraction3, and physical chemistry4,5 studies, suggest a coiled molecular structure for nucleohistone which is compatible with results from electron microscopy6–8. This communication discusses a coiled-coil structure and new experimental evidence that is compatible with it.
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PARDON, J., WILKINS, M. & RICHARDS, B. Super-helical Model for Nucleohistone. Nature 215, 508–509 (1967). https://doi.org/10.1038/215508a0
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DOI: https://doi.org/10.1038/215508a0
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