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Inhibition of Growth of Subtilis Phage SP-50 by Histones

Nature volume 215, pages 439–441 (1967)Cite this article

Abstract

BUKRINSKAYA et al.1 demonstrated the inhibitory effect of histones on the growth of fowl plague virus—one of the viruses which contains RNA. Synthesis of RNA and viral haemagglutinin in infected chicken fibroblast cells were inhibited by calf thymus histones. Recently, it was found that when histones were added they reduced the multiplication of Semliki forest virus—another virus containing RNA, and vaccinia virus, which contains DNA2,3. In all these studies chicken fibroblast cells were used. The present investigation was carried out to examine the effect of histones on the growth of subtilis phage SP-50 in bacterial cells thought to be free of histones.

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References

  1. Bukrinskaya, A. G., Gitelman, A. K., and Shapiro, I. M., Nature, 208, 557 (1965).

    Article  ADS  CAS  Google Scholar 

  2. Connolly, J. H., Nature, 212, 858 (1966).

    Article  ADS  CAS  Google Scholar 

  3. Balandin, I. G., Melnikova, I. G., Kozlova, I. A., Peterson, O. P., Masharina, I. V., and Zhdanov, V., Arch. Gesmte. Virusforsch., 18, 350 (1966).

    Article  CAS  Google Scholar 

  4. Földes, J., and Trautner, A. T., Vererbungsl., 95, 57 (1964).

    Google Scholar 

  5. Brenner, S., and Stent, G. S., Biochim. Biophys. Acta. 17, 173 (1955).

    Article  Google Scholar 

  6. Huang, R. S., Bonner, J., and Murray, K. J., J. Mol. Biol., 9, 54 (1964).

    Article  Google Scholar 

  7. Allfrey, V. G., Littau, V. C., and Mirsky, A. G., Proc. US Nat. Acad. Sci., 49, 414 (1963).

    Article  ADS  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Virology, Department of Biochemistry of University of Helsinki,

    PIRKKO POHJANPELTO

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  1. PIRKKO POHJANPELTO
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POHJANPELTO, P. Inhibition of Growth of Subtilis Phage SP-50 by Histones. Nature 215, 439–441 (1967). https://doi.org/10.1038/215439a0

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  • DOI: https://doi.org/10.1038/215439a0

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