Abstract
INVESTIGATIONS of the metabolism of Mycobacteriumleprae1 have revealed a few of the metabolic characteristics of this micro-organism. Concentrates of M. leprae prepared from lepromatous material actively oxidized 3,4-dihydroxyphenylalanine (DOPA) to pigmented products, in vitro2. Among several strains of mycobactena tested (including M. tuberculosis, M. lepraemurium, and alleged M. leprae cultures), only the leprosy bacilli obtained from infected tissues oxidized DOPA; and this specific metabolic activity has been proposed as an identification test for M. leprae3.
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PRABHAKARAN, K. Phenoloxidase of Mycobacterium leprae. Nature 215, 436–437 (1967). https://doi.org/10.1038/215436a0
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DOI: https://doi.org/10.1038/215436a0
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