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Interferon and Murine Leukaemia. III: Efficacy of Interferon Preparations administered after Inoculation of Friend Virus

Nature volume 215, pages 174–175 (1967)Cite this article

Abstract

INTERFERON has been most effective in vitro and in vivo when administered before viral inoculation, considerably less effective when inoculated at the same time as the challenge virus, and often ineffective after viral inoculation1–3. The necessity of pretreatment of cells or animals to obtain an anti-viral effect has raised doubts as to the value of interferon in the treatment of viral diseases4–5.

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Authors and Affiliations

  1. Laboratories of Viral Oncology and Pathophysiology, Institut de Recherches Scientifiques sur le Cancer, 94, Villejuif

    I. GRESSER, J. COPPEY, D. FONTAINE-BROUTY-BOYE & R. FALCOFF

  2. Groupe de Recherches sur les virus, Institut National de la Santé et de la Recherche Médicale, Hôpital Saint-Vincent de Paul, Paris

    E. FALCOFF

  3. Unité de Physiologie Cellulaire, Institut du Radium, 91, Orsay

    F. ZAJDELA

Authors
  1. I. GRESSER
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  2. J. COPPEY
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  3. D. FONTAINE-BROUTY-BOYE
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  4. R. FALCOFF
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  5. E. FALCOFF
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  6. F. ZAJDELA
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GRESSER, I., COPPEY, J., FONTAINE-BROUTY-BOYE, D. et al. Interferon and Murine Leukaemia. III: Efficacy of Interferon Preparations administered after Inoculation of Friend Virus. Nature 215, 174–175 (1967). https://doi.org/10.1038/215174a0

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  • DOI: https://doi.org/10.1038/215174a0

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