Abstract
A living isolated retina exhibits the initial fast phase, but not the later slow phase of dark adaptation. The irreversible loss of sensitivity with adaptation to bright light in this preparation is directly related to the bleaching of rhodopsin.
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References
Sickel, W., Lippman, H. G., Haschke, W., and Baumann, C., Ber. dtsch. Ophthal. Ges., 63, 316 (1961).
Sickel, W., Science, 148, 648 (1965); and in Clinical Electroretinography (edit. by Burian, H., and Jacobson, J.), 115 (Pergamon Press, Oxford and New York, 1966).
Ames, A., and Gurian, B. S., Arch. Ophthal., 70, 837 (1963).
Ames, A., in Biochemistry of the Retina (edit. by Graymore, C. N.) 22 (Academic Press, London and New York, 1965).
Rushton, W. A. H., J. Physiol., 156, 193 (1961).
Rushton, W. A. H., J. Physiol., 176, 38 (1965).
Rushton, W. A. H., J. Physiol., 176, 56 (1965).
Rushton, W. A. H., in A Symposium on Light and Life (edit. by McElroy, W. D., and Glass, B.), 706 (Johns Hopkins Press, Baltimore, 1961).
Dowling, J. E., J. Gen. Physiol., 46, 1287 (1963).
Kuhne, W., On the Photochemistry of the Retina and on Visual Purple (trans. and edit. by Foster, M.) (Macmillan, London, 1878).
Dowling, J. E., and Wald, G., Proc. US Nat. Acad. Sci., 44, 648 (1958).
Dowling, J. E., and Wald, G., Proc. US Nat. Acad. Sci., 46, 587 (1960).
Dodt, E., and Echte, K., J. Neurophysiol., 24, 427 (1961).
Wald, G., and Brown, P. K., J. Gen. Physiol., 37, 189 (1953).
Denton, E. J., and Wyllie, J. H., J. Physiol., 127, 81 (1955).
Cone, R. A., J. Gen. Physiol., 46, 1287 (1963).
Donner, K. O., and Reuter, T., Vision Res., 5, 615 (1965).
Donner, K. O., and Reuter, T., Vision Res., 7, 17 (1967).
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WEINSTEIN, G., HOBSON, R. & DOWLING, J. Light and Dark Adaptation in the Isolated Rat Retina. Nature 215, 134–138 (1967). https://doi.org/10.1038/215134a0
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DOI: https://doi.org/10.1038/215134a0
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