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Incorporation of 14C-Choline and Tritiated Inositol into Rat Adipose Tissue Phospholipid in vitro

Nature volume 215, pages 1189–1190 (1967)Cite this article

Abstract

PHOSPHATIDIC acid is known to be the only labelled phospholipid which is produced in significant amounts in rat white adipose tissue in vitro1 from 1-14C-palmitate, 1-14C- or 32P-glycerophosphate. Steinberg et al.2, on the other hand, reported that a certain amount of the radioactivity (9–25 per cent) of the total phospholipid, after incubation of adipose tissue homogenates with 1-14C-palmitate, was not in the phosphatidic acid fraction. We have investigated the problem of phospholipid biosynthesis in rat adipose tissue and have shown that, together with phosphatidic acid, phosphatidylcholine and mono-phosphoinositide are probably formed3.

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  1. Istituto di Chimica Biologica, Università di Pavia,

    GIUSEPPE PORCELLATI

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  1. GIUSEPPE PORCELLATI
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PORCELLATI, G. Incorporation of 14C-Choline and Tritiated Inositol into Rat Adipose Tissue Phospholipid in vitro. Nature 215, 1189–1190 (1967). https://doi.org/10.1038/2151189a0

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