Abstract
PARTRIDGE et al.1 observed that hydrolysis of pure insoluble elastin from bovine ligamentum nuchae by oxalic acid gave rise to soluble elastin consisting of two fractions: α-elastin with a mean molecular weight of 60,000–84,000; and β-elastin with a mean molecular weight of 5,000. Solutions of α-elastin formed a reversible coacervate phase on heating. Hall and Czerkawski2 showed that coacervation could be affected by detergents. On prolonged heating of the solutions of soluble elastin, a reconstituted product was prepared with characteristics similar in many respects to those of the original elastin3.
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References
Partrirdge, S. M., Davis, H. F., and Adair, G. S., Biochem. J., 51, 11 (1955).
Hall, D. A., and Czerkawski, J. W., Biochem. J., 80, 121 (1961).
Wood, G. C., Biochem. J., 69, 539 (1958).
Hall, D. A., in Elastolysis and Ageing (C. C. Thomas, Springfield, 1964).
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Ksiezny, S., Ardelt, W., Budzynski, A. Z., Niedzwiecka-Namyslowska, I., and Wojtecka-Lukasik, E., Acta Biochim. Polonica., 12, 327 (1965).
Gotte, L., Serafini-Fracassini, A., and Moret, V., J. Atheroscler. Res., 3, 244 (1963).
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PODRAZKY, V. Reconstitution of Elastin. Nature 215, 1162–1163 (1967). https://doi.org/10.1038/2151162a0
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DOI: https://doi.org/10.1038/2151162a0
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