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New Semi-synthetic Penicillin active against Pseudomonas pyocyanea

Abstract

Most of the semi-synthetic penicillins developed from 6-amino-penicillanic acid have little or no activity against Pseudomonas pyocyanea. α-Carboxybenzylpenicillin (carbenicillin : BRL 2064), on the other hand, is active against these organisms and seems to be almost completely non-toxic to man.

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References

  1. Knudsen, E. T., and Rolinson, G. N., Brit. Med. J., ii, 700 (1960).

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ACRED, P., BROWN, D., KNUDSEN, E. et al. New Semi-synthetic Penicillin active against Pseudomonas pyocyanea. Nature 215, 25–30 (1967). https://doi.org/10.1038/215025a0

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