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Control of a Response after Chronic Reduction of Cholinesterase

Nature volume 214, pages 629–630 (1967)Cite this article

Abstract

ABNORMAL conditioned response behaviour can follow from a reduction in the concentration of cholinesterase in rats1–3. It has also been shown that this instability in response occurs only when the incorrect or inadequate responses of an animal go unpunished. The observed deficiencies in response control disappeared when the incorrect behaviour was reinforced with aversive stimulation4,5. Here we report the effects of increasing the opportunities for free response so as to maximize any loss of response control that may follow as a consequence of a reduction in the concentration of cholinesterase.

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References

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Author notes

  1. ALAN J. RICHARDSON

    Present address: Department of Psychology, University of New England, Armidale, New South Wales

Authors and Affiliations

  1. Department of Psychology, University of Adelaide,

    PETER H. GLOW & ALAN J. RICHARDSON

Authors
  1. PETER H. GLOW
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  2. ALAN J. RICHARDSON
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GLOW, P., RICHARDSON, A. Control of a Response after Chronic Reduction of Cholinesterase. Nature 214, 629–630 (1967). https://doi.org/10.1038/214629b0

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