Abstract
EARLIER I reported1,2 the mutagenic effect of irradiated DNA in Drosophila melanogaster. In the meantime, however, negative results have been reported by Chopra3 and Seecof and Kaplan4. Khan and Alderson5 used a chemically defined medium and, working in aseptic conditions, found that whereas calf-thymus DNA, irradiated or unirradiated, is mutagenic, the process of irradiation does not enhance the mutagenic effectiveness. These authors report that they had detected “several bunches of identical (allelic) lethals in the progeny of the individual males in both DNA experiments”. They counted each bunch as a single lethal. (Here it may be remarked that it is not justified to count a bunch as a single lethal6.) Furthermore, it is not clear whether the bunches were of different sizes and whether they appeared more often with irradiated DNA than with unirradiated DNA or otherwise.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Parkash, O., Nature, 205, 312 (1965).
Parkash, O., Naturwiss., 52, 142 (1965).
Chopra, V. L., Nature, 208, 699 (1965).
Seecof, R., and Kaplan, W. D., Drosophila Information Service, 41, 101 (1966).
Khan, A. H., and Alderson, T., Nature, 208, 700 (1965).
Auerbach, C., Mutation, 49 (Oliver and Boyd, London, 1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
OM PARKASH Mutagenic Effect of Irradiated DNA in Drosophila melanogaster. Nature 214, 611–612 (1967). https://doi.org/10.1038/214611b0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/214611b0
This article is cited by
-
Transposable elements behavior following viral genomic stress inDrosophila melanogaster inbred line
Journal of Molecular Evolution (1996)
-
Genome and stresses: Reactions against aggressions, behavior of transposable elements
Genetica (1994)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
