Abstract
THE heavy (H) and light (L) chains of the IgG antibodies have been isolated and their ability to bind the antigens examined. Binding activity was found by most authors in the H chains1–3, but in other cases the binding site was found to be localized partly or wholly in the L chains4–7. An increased binding activity was observed after recombination of both chains (H + L) as compared with the isolated chains8–11.
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ZIKÁN, J., ŠTERZL, J. Binding Activity of the Antibody Heavy Chain determined by Polarography and Haemagglutination. Nature 214, 1225–1226 (1967). https://doi.org/10.1038/2141225a0
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DOI: https://doi.org/10.1038/2141225a0
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