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Proliferation of Mycobacterium tuberculosis from Mouse Lung Tissue on Various Carbon Sources

Abstract

THERE has been increasing interest in various biochemical differences between tubercle bacilli grown in vitro and those recovered from lung tissue of infected mice. During investigations of enzyme and metabolic changes in the H37Rv strain of Mycobacterium tuberculosis after transfer of bacilli from in vivo to in vitro conditions and vice versa, the proliferation of tubercle bacilli from isolated mice lung tissue (LH37Rv) was observed in defined culture media which differed in their source of carbon.

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BREZINA, O., DROBNICOVÁ, I. & DROBNICA, L. Proliferation of Mycobacterium tuberculosis from Mouse Lung Tissue on Various Carbon Sources. Nature 214, 1036–1037 (1967). https://doi.org/10.1038/2141036b0

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