Abstract
CHANGES have been reported in muscle electrolytes with age1, and several laboratories throughout the world have reported similar changes2–5. From birth to maturity the sodium and chloride content in a unit muscle mass decreases while the potassium increases. These changes are often interpreted as a function of increasing muscle cell size and a decreasing extracellular space in the muscle.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Hines, H. M., and Knowlton, G. C., Proc. Soc. Exp. Biol. and Med., 42, 133 (1939).
Yannet, H., and Darrow, D. C., J. Biol. Chem., 123, 295 (1938).
McCance, R. A., Widdowson, E. M., Quart. J. Exp. Physiol., 41, 1 (1956).
Kerpel-Fronius, E., Nagy, L., and Magyarka, B., Biol. Neonat., 6, 177 (1964).
Widdowson, E. M., and Dickenson, J. W. T., in Mineral Metabolism (edit. by Comar, C. L., and Bronner, F.), 2, part A (Academic Press, 1964).
Vernadakis, A., and Woodbury, D. M., Amer. J. Physiol., 206, 1365 (1964).
Novikova, A. I., Sechenov. Physiol. J. U.S.S.R., 50, 620 (1964).
Hazlewood, C. F., and Nichols, B. L., Fed. Proc., 25, 289 (1966).
Zierler, K. L., Amer. J. Physiol., 197, 515 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HAZLEWOOD, C., NICHOLS, B. In vitro Investigation of Resting Muscle Membrane Potential in Preweanling and Weanling Rat. Nature 213, 935–936 (1967). https://doi.org/10.1038/213935b0
Published:
Issue Date:
DOI: https://doi.org/10.1038/213935b0
This article is cited by
-
E–C coupling and contractile characteristics of mechanically skinned single fibres from young rats during rapid growth and maturation
Pflügers Archiv - European Journal of Physiology (2008)
-
Development of the electromechanical link in skeletal muscle fibers during postnatal ontogenesis of albino rats
Neuroscience Translations (1969)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.