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Activation of Honeybee Head Cholinesterase by Water-miscible Organic Solvents

Abstract

COLHOUN1 showed that many water-miscible organic solvents increased the activity of cholinesterase (ChE) preparations from the cockroach Periplaneta americana. Shatoury2,3 showed that a similar activation occurred in the case of the housefly Musca domestica, though here n-butanol only was used as “activator”, and the effect was far less marked. It has now been found that an even larger activation than that recorded by Colhoun can be achieved by addition of certain water-miscible organic solvents, notably n-butanol and n-pentanol, to ChE preparations from heads of the honeybee Apis mellifera.

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References

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LEWIS, D. Activation of Honeybee Head Cholinesterase by Water-miscible Organic Solvents. Nature 213, 205–206 (1967). https://doi.org/10.1038/213205b0

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