Abstract
TRANSPLANT studies of anterior pituitary tissue indicate that the hypothalamus exerts an inhibitory influence on the release of lactogenic hormone and that this hormone is luteotropic in the rat1. Comparable studies were undertaken as a preliminary investigation into the role of the pituitary in luteal maintenance in the hamster. Earlier studies indicate that autotransplants of anterior pituitary2,3 (1–4 days post coitum) to the cheek pouch or the kidney capsule of the pregnant hamster do not supply enough lactogenic hormone to cause the corpora lutea to secrete progesterone in amounts sufficient for nidation. It was noted2 that progesterone alone, in contrast with the rat4 which requires oestrogen for nidation, can maintain blastocysts through nidation in the ovariectomized hamster. Similarly, our results indicate that more than one allograft of anterior pituitary to the cheek pouch is necessary to influence the oestrous cycle of the hamster.
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MCDANIEL, J., DUBY, R. & BLACK, D. Influence of Multiple Anterior Pituitary Allografts on the Oestrous Cycle of the Syrian Hamster. Nature 213, 195–196 (1967). https://doi.org/10.1038/213195a0
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DOI: https://doi.org/10.1038/213195a0
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