Abstract
WE have previously shown1 that the appearance of slow alpha2-globulin among the blood serum proteins of the rat after the administration of the lipopolysaccharide (endotoxin) of Salmonella abortus equi is prevented by adrenalectomy. The slow alpha2-globulin response to this agent can be restored in the adrenalectomized rat by the administration of corticosterone. We wish to demonstrate that this adrenal cortical control is complete when certain other provoking agents or situations are used, but that the control is not complete when the provoking situation is immediately post-partum.
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References
Heim, W. G., and Ellenson, S. R., Nature, 208, 1330 (1965).
Heim, W. G., and Kerrigan, J. M., Nature, 199, 1100 (1963).
Boffa, G. A., Nadal, C., Zajdela, F., and Fine, J. M., Nature, 203, 1182 (1964).
Darcy, D. A., Brit. J. Cancer, 11, 137 (1957).
Boffa, G. A., Fine, J. M., and Zajdela, F., C.R. Acad. Sci., Paris, 225, 802 (1962).
Beaton, G. H., Selby, A. E., Veen, M. J., and Wright, A. M., J. Biol. Chem., 236, 2005 (1963).
Weimer, H. E., and Benjamin, D. C., Amer. J. Physiol., 209 (1965)
Heim, W. G., Nature, 193, 491 (1962).
Wise, R. W., Ballard, F. J., and Ezekiel, E., Comp. Biochem. Physiol., 9, 23 (1963).
Higgins, G. M., and Anderson, R. M., Arch. Path., 12, 186 (1931).
Weimer, H. E., and Benjamin, D. C., Fed. Proc., 25, 599 (1966).
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HEIM, W., ELLENSON, S. Adrenal Cortical Control of the Appearance of Rat Slow Alpha2-globulin. Nature 213, 1260–1261 (1967). https://doi.org/10.1038/2131260a0
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DOI: https://doi.org/10.1038/2131260a0
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