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Development of Immunological Capacities in Normal and Thymectomized Mice

Abstract

THE presence of thymus has been shown to be essential for the normal development of immunological capacities by a number of investigators. Antibody response and homograft immunity are the usual criteria of the immunological response. The capacity to produce antibody plaque-forming cells and thus to produce serum antibody in response to sheep erythrocyte antigen has been reported to be impaired in adult mice by neonatal thymectomy1–3. In this report the development of capacities for the production of haemolysin and homograft immunity in thymectomized mice as compared with those of sham-thymectomized control mice will be presented.

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TAKEYA, K., NOMOTO, K. Development of Immunological Capacities in Normal and Thymectomized Mice. Nature 213, 1248–1249 (1967). https://doi.org/10.1038/2131248a0

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