Abstract
A system is described for investigating the primary events involved in the induction of tumours by certain chemical carcinogens. It is based on the finding that such compounds alter the mode of growth of cells from a Chinese hamster lung tissue cell line in culture, and that the effect accompanies an ability to cause tumours when such cells are later injected into foreign host animals.
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SANDERS, F., BURFORD, B. Morphological Conversion of Cells in vitro by N-Nitrosomethylurea. Nature 213, 1171–1173 (1967). https://doi.org/10.1038/2131171a0
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DOI: https://doi.org/10.1038/2131171a0
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