Abstract
THE everted small intestine of the newborn pig, formed into sacs and incubated in a preparation of dialysed bovine colostrum, transports bovine immune lactoglobulin to the serosal surface; most of the protein transport occurs across sacs made from the middle third of the intestine1. This part of the small intestine is not outstanding in its ability to transport either water, sodium or glucose, but in other mammals this is the area for maximal transport of several amino-acids2. Amino-acids can either induce or suppress endocytosis in amoebae3 and it was these two observations which suggested that amino-acids could influence protein transport in the pig intestine.
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SMITH, M., PIERCE, A. Effect of Amino-acids on the Transport of Bovine Immune Lactoglobulin across Newborn Pig Intestine. Nature 213, 1150–1151 (1967). https://doi.org/10.1038/2131150a0
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DOI: https://doi.org/10.1038/2131150a0
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