Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Correlation between the Concentration of Adenosine Triphosphate and the Biosynthesis of Porphyrins in the Livers of Rats intoxicated with ‘Sedormid’

Nature volume 213, pages 1022–1023 (1967)Cite this article

Abstract

THE well known spontaneous and rapid decrease in the formation of excess porphyrin in several experimental porphyrias after cessation of administration of the toxic agent seemed to us to provide a particularly interesting possibility to assess the role of adenosine triphosphate (ATP) in the quantitative regulation of the biosynthesis of porphyrins. We have observed in a long series of experiments this role of ATP in vitro as well as in vivo1.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Gajdos, A., and Gajdos, Török, M., Bull. Soc. Chim. Biol., 45, 857 (1963); C.R. Soc. Biol., 157, 1178 (1963); S.A. J. Lab. Clin. Med., 9, 232 (1963); Bull. Soc. Chim. Biol., 47, 343 and 349 (1965); Nature, 207, 640 (1965).

    CAS  Google Scholar 

  2. Strehler, B. L., and Totter, J. R., in Glick, D., Methods of Biochemical Analysis, 1, 341 (Interscience, New York, 1954).

    Google Scholar 

  3. Mauzerall, D., and Granick, S., J. Biol. Chem., 219, 435 (1956).

    CAS  PubMed  Google Scholar 

  4. Rimington, C., Assoc. Clin. Path. Broadsheet, No. 21 (1958).

  5. Gajdos, A., and Gajdos-Török, M., C.R. Soc. Biol., 156, 1565 (1962); Nature, 193, 183 (1962); C.R. Soc. Biol., 157, 255 (1963); Rev. Franç, d'Etudes Clin. Biol., 8, 916 (1963); Nature, 206, 297 (1965).

    CAS  Google Scholar 

  6. Palma-Carlos, A., Palma-Carlos, L., Gajdos-Török, M., and Gajdos, A., Rev. Franç, d'Etudes Clin. Biol., 11, 284 (1966); Nature, 211, 974, 977 (1966).

    CAS  Google Scholar 

Download references

Author information

Author notes

  1. A. PALMA-CARLOS: Research fellow sponsored by Gulbenkian Foundation (Lisbonne).

Authors and Affiliations

  1. Laboratoire de Recherche, Clinique Médicale, Hôtel-Dieu, Parvis de Notre-Dame, Paris

    A. GAJDOS, M. GAJDOS-TÖRÖK, A. PALMA-CARLOS & L. PALMA-CARLOS

Authors
  1. A. GAJDOS
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. GAJDOS-TÖRÖK
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. PALMA-CARLOS
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. L. PALMA-CARLOS
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

GAJDOS, A., GAJDOS-TÖRÖK, M., PALMA-CARLOS, A. et al. Correlation between the Concentration of Adenosine Triphosphate and the Biosynthesis of Porphyrins in the Livers of Rats intoxicated with ‘Sedormid’. Nature 213, 1022–1023 (1967). https://doi.org/10.1038/2131022a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/2131022a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing