Abstract
PARTIAL hepatectomy1 and carbon tetrachloride administration2 cause similar acute changes in the morphology of the liver of rats which are much like the focal necrosis in the centrilobular and midzonal lobular areas, the centrilobular fatty infiltration and the glycogen loss, all of which are later followed by cellular regeneration. It has been suggested1 that in the case of hepatectomy or carbon tetrachloride treatment the changes result from a massive release of catecholamines which involves a drastic reduction of blood flow in the liver, an accumulation in the cells of lipids mobilized from the peripheral depots and the breakdown of the glycogen stores3.
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MOCARELLI, P., PROVINI, L. & CLERICI, E. Adrenal Catecholamine Concentration after Partial Hepatectomy. Nature 212, 715–716 (1966). https://doi.org/10.1038/212715b0
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DOI: https://doi.org/10.1038/212715b0
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