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Effect of Adrenaline, Noradrenaline and Isoprenaline on Hepatic Bile Secretion of Anaesthetized Dogs

Nature volume 212, pages 1598–1599 (1966)Cite this article

Abstract

MANY reports of the influence of adrenaline on bile secretion have been published in recent years. Engstrand1 reported an initial increase followed by a decrease, but others2–6 have reported decreased biliary output after administration of adrenaline. Ramprasad and Sirsi6 also found decreased biliary output when noradrenaline was infused. The effect of isoprenaline (isopropylarterenol), which is thought to be a specific, beta-adrenergic stimulant7 on bile secretion, does not, however, appear to have been investigated so far. The present work was undertaken to study this aspect.

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Authors and Affiliations

  1. Laboratory of Pharmacology, Department of Pharmacy, University of Nagpur, India

    A. V. KASTURE, D. S. SHINGVEKAR & A. K. DORLE

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  1. A. V. KASTURE
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  2. D. S. SHINGVEKAR
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  3. A. K. DORLE
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KASTURE, A., SHINGVEKAR, D. & DORLE, A. Effect of Adrenaline, Noradrenaline and Isoprenaline on Hepatic Bile Secretion of Anaesthetized Dogs. Nature 212, 1598–1599 (1966). https://doi.org/10.1038/2121598a0

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