Abstract
IT is well known that the contractility of muscles is suppressed after removal of the calcium ions from the extracellular liquid and that injection of a small quantity of calcium ions into a fibre of skeletal muscle induces contraction. A definite quantity of intracellular calcium ions is necessary to establish the association of actin and myosin in the presence of ATP, and, therefore, the activity of actomyosinatepase to provoke contraction1–6. During stimulation of the skeletal muscle fibre, calcium ions are taken from the extracellular liquid and are restored later7–10 No uptake of calcium has been detected during contraction in smooth muscle11,12.
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LASZT, L. Influence of Ethylenediamine Tetraacetate and Calcium Ions on Vascular Tension. Nature 212, 1587 (1966). https://doi.org/10.1038/2121587a0
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DOI: https://doi.org/10.1038/2121587a0
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