Abstract
INVESTIGATIONS of guanidines are still limited; the main cause is the absence of an accurate and practical method of determination in biological fluids. We describe here a useful method which uses the well known colorimetric Sakaguchi reaction for arginine. We discovered the suitability of this method when we attempted to investigate guanidine bases in cases of renal failure.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Pfiffner, J. J., and Myers, V. C., J. Biol. Chem., 87, 345 (1930).
Weber, C. J., Proc. Soc. Exp. Biol. Med., 24, 712 (1927).
Yatzidis, H., Proc. European Dialysis and Transplant Assoc., 1, 83 (1964).
Yatzidis, H., Néphron, 1, 310 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
YATZIDIS, H., OREOPOULOS, D., TSAPARAS, N. et al. Colorimetric Determination of Guanidines in Blood. Nature 212, 1498–1499 (1966). https://doi.org/10.1038/2121498a0
Issue Date:
DOI: https://doi.org/10.1038/2121498a0
This article is cited by
-
Untersuchungen zur Beeinflussung der Entzündungsbereitschaft durch harnpflichtige Substanzen
Research in Experimental Medicine (1975)
-
Determination of methylguanidine in serum and urine from normal and uremic subjects
Experientia (1971)
-
Zur renalen Ausscheidung von Buformin bei niereninsuffizienten Patienten
Pharmacologia Clinica (1968)
-
Evidence that methylguanidine is retained in chronic renal failure
Experientia (1968)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.