Abstract
A PASSIVE haemagglutination technique makes it possible to demonstrate high titres of antibodies against the O-antigen of the infecting E. coli strain in cases of acute pyelonephritis in childhood1. Several authors have reported that only 19S antibodies are formed in response to enterobacterial O-antigens in infants, children and adults2,3, as well as in experimental animals4. Our investigations of the agglutinating antibodies to the O-antigen of E. coli strains which cause acute pyelonephritis illustrate an antibody response usually dominated by 19S antibodies, but in some cases also including antibodies of other immunoglobulin types.
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HANSON, L., WINBERG, J. Demonstration of Antibodies of Different Immunoglobulin Types to the O-Antigen of the Infecting E. coli Strain in Infants and Children with Pyelonephritis. Nature 212, 1495–1496 (1966). https://doi.org/10.1038/2121495b0
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DOI: https://doi.org/10.1038/2121495b0
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