Abstract
ONE of the mechanisms by which catalytic activities are regulated in cells is the segregation of enzymes by membranes. In this way, enzyme activity takes place only in a circumscribed area of the cytoplasm. Segregation clearly occurs for hydrolytic enzymes (such as lysosomal enzymes), which would otherwise act indiscriminately on cytoplasmic components.
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ROMEO, D., DE BERNARD, B. Formation in vitro of a Lipoprotein Membrane masking Lysozyme Activity. Nature 212, 1491–1492 (1966). https://doi.org/10.1038/2121491a0
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DOI: https://doi.org/10.1038/2121491a0
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