Abstract
IN 1963, Hopkins et al.1 reported the accumulation of significant amounts of strontium-90 in the hair of rats which had acquired known body burdens of the radio-nuclide either by injection or in utero. They further suggested that the analysis of hair could provide a non-destructive method of measuring bone seeking radio-elements. The Davis Beagle Project offered a unique opportunity to test this hypothesis as the diet and the gut-kidney discrimination factors are well controlled and known. Accordingly, we assayed the concentration of strontium-90 in the hair of beagles while the animals were on a chronic ingestion regimen of the radionuclide, at constant ratios of strontium-90 : calcium, as well as afterwards. The concentration of strontium-90 in the hair was followed up to 1 year after we stopped feeding the diet containing strontium-90, and was correlated with the ratios of strontium-90 : calcium for plasma during the same periods.
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References
Hopkins, B. J., Tuttle, L. W., Pories, W. J., and Strain, W. H., Science, 139, 1064 (1963).
Della Rosa, R. J., Gielow, F., and Peterson, G., U.S.A.E.C., Document UCD No. 108, 37 (1963).
Ref. 2, p. 45.
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ROSA, R., PETERSON, G. & GIELOW, F. Strontium-90 in Beagle Hair. Nature 211, 777–779 (1966). https://doi.org/10.1038/211777a0
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DOI: https://doi.org/10.1038/211777a0
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